Main Mokelumne: Take Electra Road where Hwy 49 crosses the Mokleumne, just 6 miles south of Jackson.
North Fork Mokelumne: Take Hwy 88 from Jackson. Take Salt Springs Road to Salt Springs Reservoir. Tributary Roads will get you to the River. Tiger Creek is a good access hike from it's Reservoir near Amador Ranger Station. Another access point is taking Hwy 88, past the Ranger Station, to Ellis Road which will take you 11 miles down to Mokelumne River Camp.
South Fk Mokelumne: On Hwy 4, reach Camp Connell near Dorrington and take Summit Level Road (6N23). Summit Level will follow the South Fork of the Mokelumne downstream to Road 26. You'll need to take tributary logging roads to reach the river.
The name "Mokelumne" is a Native American term from the Miwok tribe meaning people of the fishnet. Most of the Mokelumne above Hwy 49 contains small Browns and Rainbows in the 8" to 14" class. The area is honeycombed with logging roads and small creeks. The main stem above Pardee Reservoir can have a lot of snow run-off until July. At that time, the pools show up well and it is quite fishable. Rainbows are planted within the stream but large wild browns come up the river and hold within the pools. The North Fork above Salt Springs Reservoir is also a good flyfishing opportunity during the early season. By July, however, the water flows greatly diminish and the fish are under considerable stress. The Mokelumne River flows into two Reservoirs below Hwy 49, the Pardee and Camanche Reservoir. Below these Reservoirs offer additional flyfishing opportunities for Steelhead and trout, generally by driftboat.